Influence of Explicit and Implicit Weight Bias on Dietary Compliance, and Stress Response in Treatment Seeking Overweight and Obese Adults
Andrea Gorman and Charles Sachs
Overweight and obesity has gained much attention as a growing health concern and researchers are now seeking to better understand the mind-body relationship. The mechanism of this relationship remains uncertain, however weight bias impacts quality of life, stress, and perhaps compliance with dietary interventions. There is a well-recognized potential for psychological variables to influence dietary intake. The objective of this study is to assess explicit weight bias towards oneself and implicit bias toward others in a treatment seeking adult population. A novel composite of these two psychological elements may enhance prediction of weight loss and weight loss maintenance success as well as shape potential interventions for bias reduction. A relationship between weight stigma and greater biochemical stress, independent of level of adiposity will also be tested. The study will also seek additional insight as to whether a 10-15% weight reduction and successful maintenance of this weight loss may affect a change in weight bias.
Effect of Modified Dietary Carbohydrate Intake on Lipoprotein Subclass Distribution and Particle Number in the Framingham State Food Study
Amy Knapp and Ann Johnson
Low density lipoprotein (LDL) subfractions containing a higher proportion of small dense LDL are associated with higher risk for coronary artery disease and is a characteristic of individuals diagnosed with the Metabolic Syndrome and insulin resistance. Diet composition affects lipoprotein particle distribution, in particular, the distribution of large and small LDL particles. Evidence in the literature suggests that a very low carbohydrate diet reduces the number of small LDL particles and favors a greater distribution of large LDL particles. The purpose of this study is to investigate whether isocaloric diets varying in carbohydrate composition (low, med, high) will affect lipoprotein particle distribution and particle number (especially LDL) independent of weight-loss. We hypothesize that due to changes in lipoprotein metabolism, VLDL, LDL, and HDL particle size and distribution and particle number will be different at the end of weigh loss and maintenance phases of the (FS)2 study.
Ruth Remington and
The effect of good nutrition on cognition is not disputed in the literature. What is not clear is the ideal composition of the diet that promotes optimum cognitive performance. This study will evaluate the effect of weight loss and three weight-loss maintenance diets on cognition in young and middle aged adults who participate in the Framingham State Food Study. Cognition will be assessed by the California Verbal Learning Test, Trail Making Test, and Digit Span Test. Participants in the parent study will be invited to enroll in this ancillary study and meet four times to complete the assessment instruments, at baseline, at randomization, at week 10 and at week 20, concurrent with the regularly scheduled assessments for the parent study. The controlled feeding of the parent study will allow for comparison of the effect of three diets with varying carbohydrate and fat ratios on cognition, and the potential to identify a dietary composition that can maximize cognitive function in adults.
Framingham State Food Study
Ancillary grant application form.
Framingham State Food Study
This funding opportunity announcement (FOA) solicited applications for funding to conduct ancillary studies in conjunction with the Framingham State Food Study (FS)2. This major research initiative will involve random assignment of 150 students, faculty and staff to 1 of 3 weight-loss maintenance diets, varying in carbohydrate and fat. Implementation of the study was planned for the 2014/5 and 2015/6 academic years, followed by a period of data analysis and interpretation. The goal of this FOA was to provide research opportunities that advance scientific knowledge by taking advantage of the infrastructure of the parent project.
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